Antioxidant supplements found to induce genetic abnormalities

A chance discovery by Cedars-Sinai researchers has shown that high doses of antioxidant nutritional supplements can increase genetic abnormalities in cells, which may predispose the supplement-takers to cancer. The study, led by Eduardo Marbán, director of the Cedars-Sinai Heart Institute, appears in the journal Stem Cells.

Marbán and his team accidentally discovered the danger of excessive antioxidant doses while seeking a way to reduce the genetic abnormalities that occurred naturally when the scientists sought to multiply human cardiac stem cells.

Stem cells are often grown in a laboratory culture composed of 20 percent oxygen, whereas cells growing inside human tissue are exposed to just 3 to 5 percent oxygen. Marbán’s team of researchers became frustrated because the higher concentration of oxygen in lab-grown stem cells resulted in 9 percent of the cells being rejected because of genetic abnormalities. “We sought to counter that oxidation problem by adding high doses of antioxidants directly to the cells,” Marbán explained. “That’s when we made the serendipitous discovery that there is a danger zone for the cells exposed to antioxidants to develop genetic abnormalities that predispose to cancer.”

Marbán stressed that the study’s finding applies only to excessive nutritional supplements and not to foods that are rich in antioxidants, such as milk, oranges, blueberries and peanuts. In recent years, multiple studies have touted the benefits of foods rich in antioxidants.

“Taking one multivitamin daily is fine, but a lot of people take way too much because they think if a little is good, a lot must be better,” warned Marbán. “That is just not the case. If you are taking 10 or 100 times the amount in a daily multivitamin, you may be predisposing your cells to developing cancer.”

Related:
Antioxidants found to impair muscle function
Scientists cast doubt on role of free radicals in aging

Source: Cedars-Sinai Medical Center

, ,

Comments are closed.

Cindy Crawford Meaningful beuty, Antioxidant Day creme SPF 20 UVA/UVB, 0.5fl oz. picture

Cindy Crawford Meaningful beuty, Antioxidant Day creme SPF 20 UVA/UVB, 0.5fl oz.

$20.30



500g(1.1LB)Antioxidant Butylated hydroxytoluene BHT picture

500g(1.1LB)Antioxidant Butylated hydroxytoluene BHT

$35.00



Grown Alchemist Detox Serum Antioxidant + 3 Complex 1oz As Pictured picture

Grown Alchemist Detox Serum Antioxidant + 3 Complex 1oz As Pictured

$30.10



R+Co Bel Air Smoothing Shampoo+Anti-oxidant Complex 8.5 Oz As Pictured picture

R+Co Bel Air Smoothing Shampoo+Anti-oxidant Complex 8.5 Oz As Pictured

$14.95



Grade A Pure Frankincense Resin Loban Arabic Gum picture

Grade A Pure Frankincense Resin Loban Arabic Gum

$15.00



Boscia Skincare Products Advertising Lapel Pin - Matcha Magic Antioxidant Mask picture

Boscia Skincare Products Advertising Lapel Pin - Matcha Magic Antioxidant Mask

$8.79



2 Hatian Tree Snail Shells (antipathogenic, antioxidant, skin healing) 0.006 gm picture

2 Hatian Tree Snail Shells (antipathogenic, antioxidant, skin healing) 0.006 gm

$8.88



Bubbl'r Sparkling Antioxidant Water | Watermelon Lime | 12oz/12pk (2-6pk) NEW  picture

Bubbl'r Sparkling Antioxidant Water | Watermelon Lime | 12oz/12pk (2-6pk) NEW

$18.89



Radical Skincare Peptide Infused Antioxidant Serum, .27 fl oz, NEW picture

Radical Skincare Peptide Infused Antioxidant Serum, .27 fl oz, NEW

$17.49



Advanced Antioxidant Vegetarian Quercetin & Vitamin C Tablets - Immune Support picture

Advanced Antioxidant Vegetarian Quercetin & Vitamin C Tablets - Immune Support

$46.54



Powered by WordPress. Designed by WooThemes